Who's your best friend? What happens when they're not a real person, but a voice in your head? Abi Appleby's eating disorder manifested as Ana, a voice that told her to eat less and exercise more until she disappeared. Abi trusted and listened to her for long enough that her loved ones noticed her changing body and behaviours. They helped her into treatment, but even there, she could still hear Ana's voice. Me, Myself & Ana tells the story of Abi's descent into anorexia nervosa, but it also shows how she finally quieted Ana - and realized that she wasn't her best friend, but an enemy that she could defeat.