Libro coxiella burnetii: recent advances and new perspectives in research of the q fever bacterium De Toman, Rudolf ; Heinzen, Robert A. ; Samuel, James

portada coxiella burnetii: recent advances and new perspectives in research of the q fever bacterium

Formato

Libro Físico

Ilustrado por

Editorial

Autor

Toman, Rudolf ; Heinzen, Robert A. ; Samuel, James E.

Año

2012

Idioma

Inglés

N° páginas

406

Encuadernación

Tapa Dura

Dimensiones

23.4 x 16.3 x 2.8 cm

Peso

0.73 kg.

ISBN

9400743149

ISBN13

9789400743144

Categorías

Enfermedades infectocontagiosas
Biología molecular
Ciencias de la computación

coxiella burnetii: recent advances and new perspectives in research of the q fever bacterium

Rudolf Toman (Ilustrado por) · Robert A. Heinzen (Ilustrado por) · James E. Samuel (Ilustrado por) · Springer · Tapa Dura

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Reseña del libro "coxiella burnetii: recent advances and new perspectives in research of the q fever bacterium"

Coxiella burnetii is the etiological agent of Q fever, a zoonotic disease found worldwide. The bacterium is a fascinating example of intracellular parasitism that has uniquely evolved to thrive in the most inhospitable of cellular compartments-the phagolysosome. Understanding how C. burnetii resists the degradative functions of this vacuole, and the host cell functions coopted for successful parasitism, are central to understanding Q fever pathogenesis. Recent achievements in glycomics and proteomics are guiding development of enhanced detection schemes for the bacterium in addition to shedding light on the host immune response to the pathogen. Several chapters survey immune functions that control or potentially exacerbate Coxiella infection and delve into correlates of protective immunity elicited by vaccination. Comparative genomics is also the foundation of chapters discussing diagnostic antigen discovery and molecular typing of the bacterium, with significance for development of new clinical, epidemiologic, and forensic tools.