Name: Development of Micro-emulsion based formulation of Nifedipine (en Inglés)
Price: 103060.00 CLP
Availability: InStock
Author: Kumar, Popin ; Upadhyaya, Kumud ; Chawla, Viney
ISBN: 9786206159209

portada Development of Micro-emulsion based formulation of Nifedipine (en Inglés)

Formato

Libro Físico

Autor

Popin Kumar

Kumud Upadhyaya

Viney Chawla

Editorial

LAP Lambert Academic Publishing

Idioma

Inglés

N° páginas

Encuadernación

Tapa Blanda

Dimensiones

22.9 x 15.2 x 0.5 cm

Peso

0.14 kg.

ISBN13

9786206159209

Categorías

Religión y creencias

Development of Micro-emulsion based formulation of Nifedipine (en Inglés)

Popin Kumar (Autor) · Kumud Upadhyaya (Autor) · Viney Chawla (Autor) · LAP Lambert Academic Publishing · Tapa Blanda

Libro Nuevo

$ 103.060

$ 143.140

Ahorras: $ 40.080

28% descuento

Envío normal

Origen: Estados Unidos (Costos de importación incluídos en el precio)

Se enviará desde nuestra bodega entre el Viernes 09 de Agosto y el Miércoles 21 de Agosto.

Lo recibirás en cualquier lugar de Chile entre 1 y 3 días hábiles luego del envío.

Reseña del libro "Development of Micro-emulsion based formulation of Nifedipine (en Inglés)"

The aim of project work was to develop Self micro-emulsified drug delivery system of nifedipine to increase the solubility in gastric environment to enhance the bioavailability. For suitable development of SMEDDS of nifedipine was studied to know the solubility in various oil, solvent and co-solvent to select the suitable oil and various components for SMEDDS formulation. Nifedipine showed the solubility in sesame oil, tween 80 and propylene glycol. solvent and co-solvent were mixed in various ratios to find the effective ratio for microemulsion formation. At least 26 were developed and only four shows the property of microemulsion which was observed by visual assessment in distilled water.Various formulations were developed and upon subjection of these trials, only trial F14 and F17 remain monophasic i.e. phase separation do not occur. Among these two trial only trial F14 show the characteristic of microemulsion i.e. showed >95 % transmittance. In that formulation oil, surfactant and co-surfactant was 4:4:2 respectively.At least three trials are carried to find the suitable ratio of various excipient in the preparation SMEDDS of nifedipine.