Name: maternal fetal transmission of human viruses and their influence on tumorigenesis (en Inglés)
Price: 238870.00 CLP
Availability: InStock
Author: Berencsi III, György
ISBN: 9789400742154

portada maternal fetal transmission of human viruses and their influence on tumorigenesis (en Inglés)

Formato

Libro Físico

Ilustrado por

György Berencsi III

Editorial

Springer

Autor

Berencsi III, György

Año

2012

Idioma

Inglés

N° páginas

464

Encuadernación

Tapa Dura

Dimensiones

23.4 x 15.6 x 2.7 cm

Peso

0.83 kg.

ISBN

9400742150

ISBN13

9789400742154

Categorías

Epidemiología y estadística médica
Oncología
Microbiología médica y virología

maternal fetal transmission of human viruses and their influence on tumorigenesis (en Inglés)

György Berencsi III (Ilustrado por) · Springer · Tapa Dura

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Reseña del libro "maternal fetal transmission of human viruses and their influence on tumorigenesis (en Inglés)"

The maternal-fetal barrier represented by the syncytiotrophoblast was shown to be formed by epigenetically regulated endogeneous retroviruses. This barrier, however, possesses certain plasticity, it can be penetrated by nanoparticles of different size-classes, by methabolites, toxic substances by unidirectional or bidirectional transport enzyme systems, intercellular transport mechanisms and by maternal antibodies, immunocomplexes including virus-antibody complexes by specific receptor cascades. Bidirectional microchimerism perfuse the fetal organism with maternal cells and the maternal organism with fetal stem cells. Chromosomally integrated viruses (human herpesvirus 6, parvoviruses) latently infected lymphotropic herpesviruses and tumour cells can be present among the microchimeric cells which can survive in the recipient organisms in gradually decreasing number for several decades. Idiotypic interactions of T-B cells enable a generalization of single antigenic experiences and allow a transgenerational learning of the nascent immune system. The latter function is driven by maternal antibodies which represent a great deal of the mother's immunological knowledge of the external world of antigens. Therefore, maternal antibodies function as transgenerational messengers.