Name: microbial efflux pumps: current research (en Inglés)
Price: 309940.00 CLP
Availability: InStock
Author: Yu, Edward W. ; Zhang, Qijing ; Brown, Melissa H.
ISBN: 9781908230218

portada microbial efflux pumps: current research (en Inglés)

Formato

Libro Físico

Ilustrado por

Edward W. Yu

Qijing Zhang

Melissa H. Brown

Editorial

Caister Academic Press Limited

Autor

Yu, Edward W. ; Zhang, Qijing ; Brown, Melissa H.

Año

2013

Idioma

Inglés

N° páginas

274

Encuadernación

Tapa Dura

Dimensiones

25.1 x 18.0 x 2.3 cm

Peso

0.78 kg.

ISBN

1908230215

ISBN13

9781908230218

Categorías

Enfermedades infectocontagiosas
Microbiología (no médica)

microbial efflux pumps: current research (en Inglés)

Edward W. Yu (Ilustrado por) · Qijing Zhang (Ilustrado por) · Melissa H. Brown (Ilustrado por) · Caister Academic Press Limited · Tapa Dura

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Reseña del libro "microbial efflux pumps: current research (en Inglés)"

Infectious diseases caused by bacteria remain a leading cause of death worldwide. Many of the antibiotics developed to combat bacterial infections have been rendered almost impotent due to the rapid evolution and spread of antibiotic resistance. A common and major resistance mechanism, the efflux system, enables bacteria to extrude structurally diverse antimicrobials, facilitating survival in toxic environments. The pumps also have important physiological functions, play major roles in bacterial pathogenesis and are distributed widely across diverse bacterial species. In addition a single species may harbour several different types of efflux systems: of these, active efflux has proven to be one of the most successful detoxification mechanisms used by both Gram-positive and -negative pathogens. Unravelling the intricacies of the microbial efflux systems is essential for the development of new strategies to overcome antimicrobial resistance. This has inspired a plethora of multidisciplinary research projects that have focused on the biochemistry, bioinformatics, structural and molecular biology of this fascinating field. With contributions from leading researchers in the field, this book reviews the most important current research and summarizes the most spectacular discoveries. Essential reading for all scientists with an interest in drug and antibiotic resistance in a range of different microorganisms.