Name: A Phenomenological Mathematical Modelling Framework for the Degradation of Bioresorbable Composites (Springer Theses) (en Inglés)
Price: 209640.00 CLP
Availability: InStock
Author: Ismael Moreno-Gomez
ISBN: 9783030049898

portada A Phenomenological Mathematical Modelling Framework for the Degradation of Bioresorbable Composites (Springer Theses) (en Inglés)

Formato

Libro Físico

Editorial

Springer

Autor

Ismael Moreno-Gomez

Año

2019

Idioma

Inglés

N° páginas

325

Encuadernación

Tapa Dura

ISBN13

9783030049898

N° edición

Categorías

Física matemática

A Phenomenological Mathematical Modelling Framework for the Degradation of Bioresorbable Composites (Springer Theses) (en Inglés)

Ismael Moreno-Gomez (Autor) · Springer · Tapa Dura

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Reseña del libro "A Phenomenological Mathematical Modelling Framework for the Degradation of Bioresorbable Composites (Springer Theses) (en Inglés)"

This book presents a generalised computational model for the degradation of resorbable composites, using analytic expressions to represent the interwoven phenomena present during degradation. It then combines this modelling framework with a comprehensive database of quantitative degradation data mined from existing literature and from novel experiments, to provide new insights into the interrelated factors controlling degradation. Resorbable composites made of biodegradable polyesters and calcium-based ceramics have significant therapeutic potential as tissue engineering scaffolds, as temporary implants and as drug-loaded matrices for controlled release. However, their degradation is complex and the rate of resorption depends on multiple connected factors such as the shape and size of the device, polymer chemistry and molecular weight, particle phase, size, volume fraction, distribution and pH-dependent dissolution properties. Understanding and ultimately predicting the degradation of resorbable composites is of central importance if we are to fully unlock the promise of these materials.