Name: Cancer Stem Cell Resistance to Targeted Therapy: 19 (Resistance to Targeted Anti-Cancer Therapeutics) (en Inglés)
Price: 124840.00 CLP
Availability: InStock
Author: Maccalli, Cristina ; Todaro, Matilde ; Ferrone, Soldano
ISBN: 9783030166267

portada Cancer Stem Cell Resistance to Targeted Therapy: 19 (Resistance to Targeted Anti-Cancer Therapeutics) (en Inglés)

Formato

Libro Físico

Ilustrado por

Editorial

Autor

Maccalli, Cristina ; Todaro, Matilde ; Ferrone, Soldano

Año

2020

Idioma

Inglés

N° páginas

256

Encuadernación

Tapa Blanda

Dimensiones

23.4 x 15.6 x 1.5 cm

Peso

0.39 kg.

ISBN13

9783030166267

N° edición

Categorías

Oncología
Inmunología
Biología molecular

Cancer Stem Cell Resistance to Targeted Therapy: 19 (Resistance to Targeted Anti-Cancer Therapeutics) (en Inglés)

Cristina Maccalli (Ilustrado por) · Matilde Todaro (Ilustrado por) · Soldano Ferrone (Ilustrado por) · Springer · Tapa Blanda

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Origen: Estados Unidos (Costos de importación incluídos en el precio)

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Reseña del libro "Cancer Stem Cell Resistance to Targeted Therapy: 19 (Resistance to Targeted Anti-Cancer Therapeutics) (en Inglés)"

This book represents an up-dated summary of the state of the art of the characterization of cancer stem cell/ cancer initiating cell (CSC/CIC) properties. An overview of the definition and biological properties of CSCs/CICs as well as the role of these cells in determining the resistance to standard and immune-based therapies is provided. It also discusses limitations in the achievement of a definitive biological characterization of CSCs/CICs due to their high extent of plasticity and heterogeneity that is also mutually driven by the interaction of these cells with the tumor microenvironment. The limitations in targeting CSCs/CICs with immunotherapy are also explained together with explorative combination approaches that could increase the susceptibility of these cells to the recognition by immune cells. This book is conceived for a broad audience, including students, teachers, scientific experts. The critical revision of available results in terms of immunological profile of CSCs/CICs and the efficacy in targeting these cells by immunological approaches, results in a comprehensive and up to date recapitulation of the field and provides interesting suggestions on how to focus future investigations in order to assess the role of CSCs/CICs as prognostic and predictive biomarkers of responsiveness to therapies for cancer patients.