Name: Cancer Stem Cell Resistance to Targeted Therapy (en Inglés)
SKU: 57174145
Price: 108630.00 CLP
Availability: InStock
Author: Maccalli, Cristina ; Todaro, Matilde ; Ferrone, Soldano
ISBN: 9783030166236

portada Cancer Stem Cell Resistance to Targeted Therapy (en Inglés)

Cancer Stem Cell Resistance to Targeted Therapy (en Inglés)

Formato

Libro Físico

Editorial

Springer

Autor

Maccalli, Cristina ; Todaro, Matilde ; Ferrone, Soldano

Idioma

Inglés

N° páginas

256

Encuadernación

Tapa Dura

Dimensiones

23.4x15.6x1.8 cm

Peso

0.57 kg.

ISBN13

9783030166236

Categorías

Oncología
Inmunología
Biología molecular

Cancer Stem Cell Resistance to Targeted Therapy (en Inglés)

Maccalli, Cristina ; Todaro, Matilde ; Ferrone, Soldano (Autor) · Springer · Tapa Dura

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Reseña del libro "Cancer Stem Cell Resistance to Targeted Therapy (en Inglés)"

This book represents an up-dated summary of the state of the art of the characterization of cancer stem cell/ cancer initiating cell (CSC/CIC) properties. An overview of the definition and biological properties of CSCs/CICs as well as the role of these cells in determining the resistance to standard and immune-based therapies is provided. It also discusses limitations in the achievement of a definitive biological characterization of CSCs/CICs due to their high extent of plasticity and heterogeneity that is also mutually driven by the interaction of these cells with the tumor microenvironment. The limitations in targeting CSCs/CICs with immunotherapy are also explained together with explorative combination approaches that could increase the susceptibility of these cells to the recognition by immune cells. This book is conceived for a broad audience, including students, teachers, scientific experts. The critical revision of available results in terms of immunological profile of CSCs/CICs and the efficacy in targeting these cells by immunological approaches, results in a comprehensive and up to date recapitulation of the field and provides interesting suggestions on how to focus future investigations in order to assess the role of CSCs/CICs as prognostic and predictive biomarkers of responsiveness to therapies for cancer patients.