Name: Caring for the Individual Patient. Understanding Heterogeneous Treatment Effects
SKU: 65786990
Price: 21950.00 CLP
Availability: InStock
Author: National Academy of Medicine;Mahnoor Ahmed;Jessica Paulus;David Kent;Danielle Whicher;The Learning Health System Series
ISBN: 9780309705189

portada Caring for the Individual Patient. Understanding Heterogeneous Treatment Effects

Caring for the Individual Patient. Understanding Heterogeneous Treatment Effects

Formato

Libro Físico

Editorial

National Academies Press

Autor

National Academy of Medicine;Mahnoor Ahmed;Jessica Paulus;David Kent;Danielle Whicher;The Learning Health System Series

Año

2023

N° páginas

120

Encuadernación

Tapa Blanda

Dimensiones

22.9x15.2x2.5 cm

ISBN13

9780309705189

Caring for the Individual Patient. Understanding Heterogeneous Treatment Effects

National Academy Of Medicine;Mahnoor Ahmed;Jessica Paulus;David Kent;Danielle Whicher;The Learning Health System Series (Autor) · National Academies Press · Tapa Blanda

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Reseña del libro "Caring for the Individual Patient. Understanding Heterogeneous Treatment Effects"

Evidence-based medicine arose from a clear need and represents a major advance in the science of clinical decision making. Despite broad acceptance of evidence-based medicine, however, a fundamental issue remains unresolved: evidence is derived from groups of people, yet medical decisions are made by and for individuals. Despite persistent assertions from clinicians that determining the best therapy for each patient is a more complicated endeavor than just picking the best treatment on average, traditional approaches have been overly reliant on the average effects estimated from the outcomes of clinical trials. This Special Publication is based on a workshop, held by the National Academy of Medicine, that considered patient and stakeholder perspectives on the importance of understanding heterogeneous treatment effects (HTE) and best practices for implementing clinical programs that take HTE into account. For evidence to be more applicable to individual patients, we need to combine methods for strong causal inference (first and foremost, randomization) with methods for prediction that permit inferences about which particular patients are likely to benefit and which are not. Better population-based outcomes will only be realized when we understand more completely how to treat patients as the unique individuals they are. Table of ContentsFront MatterSummary1 Introduction2 The Promise of Personalized Evidence-Based Medicine3 Patient Perspectives of the Significance of Understanding Heterogeneous Treatment Effects4 New Methods for the Prediction of Treatment Benefit and Model Evaluation5 Next Steps for Implementation6 A Research Agenda for Personalizing Care and Improving Treatment OutcomesReferencesAppendix A: GlossaryAppendix B: Workshop Participants, Web Participants, and StaffAppendix C: Workshop Agenda