Name: Extended Release Tablet of Glipizide (en Inglés)
Price: 90300.00 CLP
Availability: InStock
Author: Pandya, Shreya ; Dave, Pooja ; Pujara, Naisarg
ISBN: 9786202815109

portada Extended Release Tablet of Glipizide (en Inglés)

Formato

Libro Físico

Autor

Shreya Pandya

Pooja Dave

Naisarg Pujara

Editorial

LAP Lambert Academic Publishing

Idioma

Inglés

N° páginas

108

Encuadernación

Tapa Blanda

Dimensiones

22.9 x 15.2 x 0.7 cm

Peso

0.17 kg.

ISBN13

9786202815109

Categorías

Farmacología

Extended Release Tablet of Glipizide (en Inglés)

Shreya Pandya (Autor) · Pooja Dave (Autor) · Naisarg Pujara (Autor) · LAP Lambert Academic Publishing · Tapa Blanda

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Origen: Estados Unidos (Costos de importación incluídos en el precio)

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Reseña del libro "Extended Release Tablet of Glipizide (en Inglés)"

The present investigation was to formulate and evaluate extended release tablet of glipizide using natural gum for the treatment of type II diabetes. Extended release tablet was prepared by employing hydrophobic diluents (DCP) and hydrophilic diluents (starch). Experimental work done: Preformulation studies and drug excipient profile were carried out for glipizide and dammar gum. Different batches of glipizide extended release tablets were prepared by using dicalcium phosphate and starch as diluents by wet granulation technique and direct compression method. Seven batches were made by changing concentration of dammar gum and change diluents in formulation. A physicochemical properties of dammar gum were evaluated such as acid value, iodine value, melting point, molecular weight. Result and Discussion: Results of preformulation study were satisfactory as no interaction was observed between glipizide and dammar gum by FTIR and DSC. All the pre and post compression parameters were tested. In vitro drug release profiles were examined, and compared with marketed product. The drug release of D5 batch is extended upto 98.22% in 12hr, and it follows korsmeyer peppas model.