Name: I Domains in Integrins (Molecular Biology Intelligence Unit) (en Inglés)
SKU: 3411246
Price: 159910.00 CLP
Availability: InStock
Author: Donald Gullberg
ISBN: 9780306478369

portada I Domains in Integrins (Molecular Biology Intelligence Unit) (en Inglés)

I Domains in Integrins (Molecular Biology Intelligence Unit) (en Inglés)

Formato

Libro Físico

Editorial

Springer

Autor

Donald Gullberg

Año

2003

Idioma

Inglés

N° páginas

200

Encuadernación

Tapa Dura

ISBN

0306478366

ISBN13

9780306478369

N° edición

2003

Categorías

Bioquímica

I Domains in Integrins (Molecular Biology Intelligence Unit) (en Inglés)

Donald Gullberg (Autor) · Springer · Tapa Dura

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Reseña del libro "I Domains in Integrins (Molecular Biology Intelligence Unit) (en Inglés)"

In vertebrates, the integrin family includes 24 members. As the alpha-chains were sequenced, some were observed to have an inserted domain similar to the A domain in several matrix and complement proteins. This inserted ligand binding domain is interactive and was called the I domain in integrins. More recently structural data have shown that an integrin beta-chain also contains an I domain. Nine of the currently known 18 alpha-chains contain an I domain. This book systematically goes through the current knowledge about these integrins, including the newest additions to the integrin family, the collagen-binding alpha10beta1 and alpha11beta1 integrins. The book discusses ligand binding, signalling properties, knock-out phenotypes and possible involvement in disease. This book comprehensively reviews the current knowledge about I domains in integrins and will serve as a useful reference book for scientists in this field.