Name: Magnetic Fluid Hyperthermia: Magnetic Relaxation Simulation, Modeling of Nanoparticle Uptake Inside Pancreatic Tumor Cells and in Vitro Efficacy (en Inglés)
Price: 91140.00 CLP
Availability: InStock
Author: Ulrich Engelmann
ISBN: 9783945954584

portada Magnetic Fluid Hyperthermia: Magnetic Relaxation Simulation, Modeling of Nanoparticle Uptake Inside Pancreatic Tumor Cells and in Vitro Efficacy (en Inglés)

Magnetic Fluid Hyperthermia: Magnetic Relaxation Simulation, Modeling of Nanoparticle Uptake Inside Pancreatic Tumor Cells and in Vitro Efficacy (en Inglés)

Formato

Libro Físico

Editorial

Infinite Science Publishing

Autor

Ulrich Engelmann

Idioma

Inglés

N° páginas

302

Encuadernación

Tapa Blanda

ISBN13

9783945954584

Magnetic Fluid Hyperthermia: Magnetic Relaxation Simulation, Modeling of Nanoparticle Uptake Inside Pancreatic Tumor Cells and in Vitro Efficacy (en Inglés)

Ulrich Engelmann (Autor) · Infinite Science Publishing · Tapa Blanda

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Reseña del libro "Magnetic Fluid Hyperthermia: Magnetic Relaxation Simulation, Modeling of Nanoparticle Uptake Inside Pancreatic Tumor Cells and in Vitro Efficacy (en Inglés)"

Magnetic fluid hyperthermia (MFH) uses magnetic nanoparticles (MNP) to transform the energy of an alternating magnetic field into heat via magnetic relaxation. This enables organ-confined cancer treatment by delivering cell-damaging temperatures higher than 43 C inside tumors. However, MNP-cell interaction restricts MNP mobility and causes MNP agglomeration, severely limiting the MNP heating behavior. Based on in vitro experiments, this book addresses the applicability of MFH to pancreatic tumor cells and discusses optimizations of intracellular MNP heating for clinical application. The impact of MNP-cell interaction on heating efficiency is quantified and compared to MNP systems mimicking intracellular conditions. Besides, Monte-Carlo simulation of MNP magnetic relaxation is used to predict optimal field parameters and MNP properties to maximize MFH efficiency under medical constraints.