Name: Polycomb Group Proteins (en Inglés)
SKU: 56727733
Price: 123830.00 CLP
Availability: InStock
Author: Vincenzo Pirrotta
ISBN: 9780128097373

portada Polycomb Group Proteins (en Inglés)

Formato

Libro Físico

Editorial

Academic Press

Autor

Vincenzo Pirrotta

Idioma

Inglés

N° páginas

372

Encuadernación

Tapa Dura

ISBN13

9780128097373

N° edición

Polycomb Group Proteins (en Inglés)

Vincenzo Pirrotta (Autor) · Academic Press · Tapa Dura

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Reseña del libro "Polycomb Group Proteins (en Inglés)"

Polycomb Group Proteins is a comprehensive volume detailing the mechanisms that are key to the management of genome function in many different contexts, from embryonic stem cells to terminal differentiation. The book discusses the regulation of cell lineages, cell proliferation, apoptosis, X chromosome inactivation, and most major genome programming choices. In the last few years, the biochemical understanding of PRC1-type complexes has greatly expanded in terms of the number of components involved and the intricacies of their interactions. The functionalities of these various complexes and their components are not all well understood, but recent work has shown an important division of labor and roles in the recruitment of stable binding in the ability to lay the groundwork of histone modifications and in the epigenetic maintenance of repressed states. In an effort to provide clarity in this topical research area, the book provides a cluster of chapters that deal with variant PRC1 complexes, their taxonomy, their components, their interactions, and what is known of their functions.