Name: retrotransposition, diversity and the brain (en Inglés)
Price: 135580.00 CLP
Availability: InStock
Author: Gage, Fred H.
ISBN: 9783642094378

portada retrotransposition, diversity and the brain (en Inglés)

Formato

Libro Físico

Ilustrado por

Fred H. Gage

Editorial

Springer

Autor

Gage, Fred H.

Año

2010

Idioma

Inglés

N° páginas

123

Encuadernación

Tapa Blanda

Dimensiones

23.4 x 15.6 x 0.7 cm

Peso

0.20 kg.

ISBN

3642094376

ISBN13

9783642094378

Categorías

Génetica médica
Neurología y neurofisiología clínicas
Genética (no médica)
Neurociencias

retrotransposition, diversity and the brain (en Inglés)

Fred H. Gage (Ilustrado por) · Springer · Tapa Blanda

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Origen: Estados Unidos (Costos de importación incluídos en el precio)

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Reseña del libro "retrotransposition, diversity and the brain (en Inglés)"

The human brain is remarkably complex, permitting sophisticated behavioural rep- toires, such as languages, tool use, self-awareness, symbolic thought, cultural learning and consciousness. Each human being is different, due in part to the uniqueness of the neuronal heterogeneity and interconnections in our brains. Brain complexity and neuronal diversity are strongly related. The diversity of single neurons provides the underpinnings for how neuronal circuits operate. How and when neuronal diversity is generated, both in embryonic and adult neurogenesis, remain unknown. In the immune system, the highly diverse array of antigen receptors can be - tributed to the stochastic nature of the recombination process in somatic precursor cells, causing permanent changes in DNA and gene expression. This diverse population is then the target of selective processes that favor the correct antigen-receptor match and eliminate those with inadequate speci?cities, accounting for the rapid kinetics and immense diversity observed in vivo. Evidence for a possible similarity between the nervous and immune systems came from studies with mice de?cient in DNA double strand break (DSB) repair. Lessons learned from the discovery of the mechanism for diversityinthe immune system maybe usefultothe investigation ofthe mechanism of diversity in neurons.