Name: Simultaneous Estimation of Cefixime and Linezolid (en Inglés)
SKU: 57261992
Price: 55680.00 CLP
Availability: InStock
Author: Chaki, Imran ; Patel, Pratik ; Pujara, Naisarg
ISBN: 9786139454754

portada Simultaneous Estimation of Cefixime and Linezolid (en Inglés)

Simultaneous Estimation of Cefixime and Linezolid (en Inglés)

Formato

Libro Físico

Autor

Naisarg Pujara

Imran Chaki

Pratik Patel

Editorial

LAP Lambert Academic Publishing

Idioma

Inglés

N° páginas

Encuadernación

Tapa Blanda

Dimensiones

22.9x15.2x0.5 cm

Peso

0.14 kg.

ISBN13

9786139454754

Categorías

Farmacología

Simultaneous Estimation of Cefixime and Linezolid (en Inglés)

Naisarg Pujara (Autor) · Imran Chaki (Autor) · Pratik Patel (Autor) · LAP Lambert Academic Publishing · Tapa Blanda

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Reseña del libro "Simultaneous Estimation of Cefixime and Linezolid (en Inglés)"

Development and validation of simple, precise, accurate, economical and sensitive HPLC assay method for the estimation of Cefixime and Linezolid in tablet dosage form. A chromatographic separation was achieved with a Hypersil BDS C18 (250mm,4.6mm,5 m) analytical column. A Mixture of Phosphate Buffer (3.0 pH): methanol (40:60, v/v) was used as the mobile phase, at a flow rate of 1.0 ml/min and detector wavelength at 277 nm. The retention time of Cefixime and linezolid was found to be 3.76 and 6.55 min respectively. Theoretical plates was 6896 and 4626 respectively and Tailing factor was 1.32 and 1.28. The linear ranges was 5-15 for cefixime and 15-45 μg/ml for linezolid, and the correlation coefficient was 0.999 for both drugs. The relative standard deviation was found to be less than 2%. A simple, precise, accurate, economical and sensitive HPLC assay method have been developed and validated for the estimation of Cefixime and linezolid in tablet dosage form. All method validation parameters lie within its acceptance crieteria as per ICH Q2(R1) guideline.