Name: Synthesis and Antimicrobial activity of some Chrome-2-one derivatives (en Inglés)
Price: 64780.00 CLP
Availability: InStock
Author: Padhy, Gopal Krishna ; Bhosale, S. H.
ISBN: 9786203410921

portada Synthesis and Antimicrobial activity of some Chrome-2-one derivatives (en Inglés)

Synthesis and Antimicrobial activity of some Chrome-2-one derivatives (en Inglés)

Formato

Libro Físico

Autor

Gopal Krishna Padhy

S. H. Bhosale

Editorial

LAP Lambert Academic Publishing

Idioma

Inglés

N° páginas

104

Encuadernación

Tapa Blanda

Dimensiones

22.9 x 15.2 x 0.6 cm

Peso

0.16 kg.

ISBN13

9786203410921

Categorías

Química

Synthesis and Antimicrobial activity of some Chrome-2-one derivatives (en Inglés)

Gopal Krishna Padhy (Autor) · S. H. Bhosale (Autor) · LAP Lambert Academic Publishing · Tapa Blanda

Libro Nuevo Importado *

Envío: 17 a 24 días háb.

$ 129.560$ 64.780

-50%

* Costos de importación incluídos en el precio ✅

Libro Nuevo

Quedan 10 unidades

$ 64.780

Se enviará desde nuestra bodega entre el Lunes 27 de Abril y el Jueves 07 de Mayo

Agregar a lista de deseos

Reseña del libro "Synthesis and Antimicrobial activity of some Chrome-2-one derivatives (en Inglés)"

The aim of the undertaken research work was to synthesise molecules, which could have capability of inhibiting growth of bacteria and fungi. Pechmann and Duisberg method was used to synthesise 7-hydroxy-4-methyl chromen-2-one. Ethyl 2-(4-methyl-2-oxo-2H-chromen-7-yloxy) acetate was synthesized by the reaction between ethylchloroacetate and 7-hydroxy-4-methyl chromen-2-one in presence of acetone and anhydrous K2CO3. 4-Methyl-2-oxo-2H-chromen-7-yloxy)-acetic acid hydrazide (3) was synthesized from Ethyl 2-(4-methyl-2-oxo-2H-chromen-7-yloxy) acetate and 85% NH2 NH2 .H2O in ethanol as a solvent. Compounds (4a-4l), were synthesised by reaction of compound (3) with various aldehydes and isatin in acetic acid-ethanol as solvents. The sharp melting points, TLC, HPTLC and IR & 1H NMRspectral analysis confirmed the purity and homogeneity of all the title compounds. The synthesised compounds were obtained in solid state in yield varying from 61 to 88 %. In case of antibacterial activity compound 4e was found to be the most active compound among the entire series against Staphylococcus aureus.In case of antifungal activity compound 4l was found to be the most active.