Name: The Multitasking Molecular Chaperone Hsp60: Structure, Function, and Impact on Health and Disease (en Inglés)
SKU: 63294720
Price: 184780.00 CLP
Availability: InStock
Author: Cappello Francesco,Conway De Macario Everly,Jl Macario Alberto
ISBN: 9780443239960

portada The Multitasking Molecular Chaperone Hsp60: Structure, Function, and Impact on Health and Disease (en Inglés)

The Multitasking Molecular Chaperone Hsp60: Structure, Function, and Impact on Health and Disease (en Inglés)

Formato

Libro Físico

Editorial

Academic Press

Autor

Cappello Francesco,Conway De Macario Everly,Jl Macario Alberto

Idioma

Inglés

N° páginas

324

Encuadernación

Tapa Blanda

ISBN13

9780443239960

N° edición

The Multitasking Molecular Chaperone Hsp60: Structure, Function, and Impact on Health and Disease (en Inglés)

Cappello Francesco,Conway De Macario Everly,Jl Macario Alberto (Autor) · Academic Press · Tapa Blanda

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Reseña del libro "The Multitasking Molecular Chaperone Hsp60: Structure, Function, and Impact on Health and Disease (en Inglés)"

The Multitasking Molecular Chaperone Hsp60: Structure, Function, and Impact on Health and Disease provides an overview of this key component of the Chaperone System (CS). The book covers various areas of medicine in which Hsp60 chaperonopathies have been identified. Various chapters discuss the Hsp60 structure, localization, functions, and participation in disease mechanisms both genetic and acquired, focusing on humans but also presenting data obtained from pro- and eukaryotic experimental models. The main goal is to provide information accessible to all healthcare professionals in a way that can be understood by nonspecialists and that would stimulate clinical and pathological detection of Hsp60 chaperonopathies. Molecular mechanisms are briefly described with the purpose of illuminating roads toward accurate diagnosis, treatment, and patient monitoring. Consequently, the possibility of developing/applying chaperonotherapy centered on Hsp60, as a therapeutic tool or target, is analyzed in many sections of this book, across a variety of medical specialties. Over the last several years, the importance of the CS as a physiological system has been brought to prominence and its roles in health and disease made clear. The molecular chaperones, including Hsp60, are the key components of the CS that are typically cytoprotective, but they can also be etiopathogenic factors, causing diseases named chaperonopathies.