Name: Synthesis & Study Biological Activity of New Phthalimide Derivatives (en Inglés)
Price: 93510.00 CLP
Availability: InStock
Author: Hashim, Asaad ; Musa, Naji ; Radhi, Rua
ISBN: 9786200499684

portada Synthesis & Study Biological Activity of New Phthalimide Derivatives (en Inglés)

Formato

Libro Físico

Autor

Asaad Hashim

Naji Musa

Rua Radhi

Editorial

LAP Lambert Academic Publishing

Idioma

Inglés

N° páginas

Encuadernación

Tapa Blanda

Dimensiones

22.9 x 15.2 x 0.6 cm

Peso

0.15 kg.

ISBN13

9786200499684

Categorías

Química

Synthesis & Study Biological Activity of New Phthalimide Derivatives (en Inglés)

Asaad Hashim (Autor) · Naji Musa (Autor) · Rua Radhi (Autor) · LAP Lambert Academic Publishing · Tapa Blanda

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Reseña del libro "Synthesis & Study Biological Activity of New Phthalimide Derivatives (en Inglés)"

The research involves synthesis of some new aminoacetylenic derivatives of phthalimide. The phthalimide in this study served as starting material and was converted to the corresponding potassium salt through reaction with potassium hydroxide. The alkylation of the imide salt with the propargyl bromide afforded the desired N-propynylphthalimide (A1). The Mannich reaction (three componenets in one pot reaction) was carried out by using the N-propynylphthalimide (A1), formaldehyde, benzaldehyde and some of its derivatives, as well as morpholine or piperidine which are taken as secondary amines, in the presence of peroxide free dioxane and a catalytic amount of cuprous chloride under various basic, acidic, solvent and temperature conditions, resulted in formation of a novel aminoacetylenic Isoindoline-1,3-dione derivatives (A2-A12).